18
View
Open Access Peer-Reviewed|
ARTIGO ORIGINAL

Progressive systemic sclerosis: high-resolution computed tomography findings

Esclerose sistêmica progressiva: aspectos na tomografia computadorizada de alta resolução

Emerson L. Gasparetto, Rodrigo Pimenta, César Inoue, Sérgio E. Ono, Dante L. Escuissato



ABSTRACT

OBJECTIVE: To describe the high-resolution computed tomography findings in the lung of patients with systemic sclerosis, independently of the respiratory symptoms. MATERIALS AND METHODS: Seventy-three high-resolution computed tomography scans of 44 patients with clinical diagnosis of systemic sclerosis were reviewed and defined by the consensus of two radiologists. RESULTS: Abnormalities were seen in 91.8% (n = 67) of the scans. The most frequent findings were reticular pattern (90.4%), ground-glass opacities (63%), traction bronchiectasis and bronchiolectasis (56.2%), esophageal dilatation (46.6%), honeycombing pattern (28.8%) and signs of pulmonary hypertension (15.6%). In most cases the lesions were bilateral (89%) and symmetrical (58.5%). The lesions were predominantly located in the basal (91.2%) and peripheral (92.2%) regions. CONCLUSION: In the majority of the patients, progressive systemic sclerosis can cause pulmonary fibrosis mainly characterized by reticular pattern with basal and peripheral distribution on high-resolution computed tomography.

Keywords: High-resolution computed tomography, Progressive systemic sclerosis, Reticular pattern

RESUMO

OBJETIVO: Descrever os achados de tomografia computadorizada de alta resolução de pacientes com esclerose sistêmica pulmonar, independentemente dos sintomas respiratórios. MATERIAIS E MÉTODOS: Foram revisados 73 exames de tomografia computadorizada de alta resolução de 44 pacientes com diagnóstico de esclerodermia estabelecido através de critérios clínicos e laboratoriais. Os exames foram revisados por dois radiologistas, que estabeleceram os achados por consenso. RESULTADOS: Em 91,8% (n = 67) dos exames observaram-se alterações. Os principais achados foram lesões de padrão reticular (90,4%), opacidades em vidro-fosco (63%), bronquiectasias e bronquiolectasias de tração (56,2%), dilatação esofagiana (46,6%), faveolamento (28,8%) e sinais de hipertensão pulmonar (15,6%). Na maioria dos casos as lesões eram bilaterais (89%) e simétricas (58,5%). Quanto à localização, houve predomínio de lesões basais (91,2%) e periféricas (92,2%). CONCLUSÃO: A esclerose sistêmica progressiva acarreta fibrose pulmonar na maioria dos pacientes, caracterizada principalmente por lesão reticular basal e periférica.

Palavras-chave: Tomografia computadorizada de alta resolução, Esclerose sistêmica pulmonar, Padrão reticular


THE CONTENT OF THIS ARTICLE IS NOT AVAILABLE FOR THIS FORMAT.


Creative Commons License
This work is licensed under an Attribution 4.0 International License (CC BY 4.0), effective June 9, 2022. Previously, the journal was licensed under a Creative Commons Attribution - Non-Commercial - Share Alike 4.0 International License.

Site Map



  • SPONSORED BY

Av.Paulista, 37 - 7° andar - Conj. 71 - CEP 01311-902 - São Paulo - SP - Brazil - Phone: (11) 3372-4554 - Fax: (11) 3372-4554

© All rights reserved 2025 - Radiologia Brasileira