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Massive intracranial calcifications in a patient with systemic lupus erythematosus

Calcificações intracranianas maciças em um paciente com lúpus eritematoso sistêmico

Emerson L. Gasparetto, Sergio E. Ono, Arnolfo de Carvalho Neto



ABSTRACT

Central nervous system involvement is frequently reported in patients with systemic lupus erythematosus. Computed tomography and magnetic resonance imaging studies usually show brain atrophy, cerebral infarction and/or intracranial bleeding. Extensive intracranial calcification in patients with systemic lupus erythematosus is rare. We report a case of a patient with systemic lupus erythematosus who presented with seizures and massive basal ganglia calcification and mild calcifications in the frontal lobes, seen on the brain computed tomography scan. Magnetic resonance imaging showed hyperintensity on FLAIR images and hypointense signals on T2* gradient echo images in the basal ganglia.

Keywords: Systemic lupus erythematosus, Intracranial calcification, Computed tomography

RESUMO

O envolvimento do sistema nervoso central em pacientes com lúpus eritematoso sistêmico é freqüentemente relatado. Os exames de tomografia computadorizada e ressonância magnética demonstram achados como atrofia cerebral, infarto cerebral e/ou hemorragia intracraniana. Calcificações intracranianas maciças em pacientes com lúpus eritematoso sistêmico são raras. Os autores apresentam um paciente com lúpus eritematoso sistêmico e crises convulsivas, cuja tomografia computadorizada demonstrou extensas calcificações nos gânglios da base e focos de calcificação nos lobos frontais. A ressonância magnética revelou imagens hiperintensas na seqüência FLAIR e hipointensas em gradiente eco T2* na topografia dos gânglios da base.

Palavras-chave: Lúpus eritematoso sistêmico, Calcificação intracraniana, Tomografia computadorizada


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This work is licensed under an Attribution 4.0 International License (CC BY 4.0), effective June 9, 2022. Previously, the journal was licensed under a Creative Commons Attribution - Non-Commercial - Share Alike 4.0 International License.

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